- X (GB)
- X The Ball (Arcade)
- X-Bladez: Inline Skater (GBA)
- X-Force Genesis (Switch eShop)
- X-Force Under Attack (Switch eShop)
- X-Men (Arcade)
- X-Men Legends (GCN)
- X-Men Legends II: Rise of Apocalypse (GCN)
- X-Men Origins: Wolverine (DS)
- X-Men vs. Street Fighter (Arcade)
- X-Men: Children of the Atom (Arcade)
- X-Men: Destiny (Wii)
- X-Men: Mutant Academy (GBC)
- X-Men: Mutant Wars (GBC)
- X-Men: Next Dimension (GCN)
- X-Men: The Official Game (DS)
- X-Men: The Official Game (GCN)
- X-Men: Wolverine's Rage (GBC)
- X-Morph: Defense (Switch eShop)
- X-Out: Resurfaced (Switch eShop)
- X-Perts (MD)
- X-Scape (DSiWare)
- X2: Wolverine's Revenge (GCN)
- XALADIA: Rise of the Space Pirates X2 (Switch eShop)
- Xanchuchamel (Switch eShop)
- Xatrom Command (Switch eShop)
- Xavier (Wii U eShop)
- XCOM 2 Collection (Switch)
- XDR: X-Dazedly Ray (MD)
- XEL (Switch eShop)
- Xelan Force (Switch eShop)
- Xena: Warrior Princess (GBC)
- Xena: Warrior Princess: The Talisman of Fate (N64)
- Xeno Crisis (MD)
- Xeno Crisis (Switch)
- Xenoblade Chronicles (Wii)
- Xenoblade Chronicles 2 (Switch)
- Xenoblade Chronicles 2: Torna - The Golden Country (Switch eShop)
- Xenoblade Chronicles 3 (Switch)
- Xenoblade Chronicles 3: Future Redeemed (Switch eShop)
- Xenoblade Chronicles 3D (New 3DS)
- Xenoblade Chronicles X (Wii U)
- Xenoblade Chronicles X: Definitive Edition (Switch)
- Xenoblade Chronicles: Definitive Edition (Switch)
- Xenogunner (Switch eShop)
- Xenon 2 Megablast (GB)
- Xenon Racer (Switch)
- Xenon Valkyrie+ (Switch eShop)
- Xenoraid (Switch eShop)
- XenoRaptor (Switch eShop)
- Xenosaga I & II (DS)
- Xeodrifter (3DS eShop)
- Xeodrifter (Switch eShop)
- Xeodrifter (Wii U eShop)
- Xevious (Arcade)
- Xevious (NES)
- XG Blast (DS)
- XGRA: Extreme-G Racing Association (GCN)
- Xiaolin Showdown (DS)
- Xiaomei and the Flame Dragon's Fist (Switch eShop)
- Xicatrice (Switch)
- XIII (GCN)
- XIII (Switch)
- Xiizeal (Switch eShop)
- Xmas Puzzle (WiiWare)
- XMas Toy Merge (Switch eShop)
- Xonix (Switch eShop)
- Xposed Switched (Switch eShop)
- Xtreme Club Racing (Switch eShop)
- Xtreme Sports (GBC)
- Xtreme Sports (Switch eShop)
- Xtreme Wheels (GBC)
- XType Plus (Wii U eShop)
- Xuan Yuan Sword 7 (Switch)
- Xuan Yuan Sword Mystic RPG Bundle (Switch eShop)
- Xuan Yuan Sword: Mists Beyond the Mountains (Switch eShop)
- Xylophone (Switch eShop)